FASTKD3 Antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q14CZ7 |
Other Accession | NM_024091, NP_076996 |
Reactivity | Human |
Predicted | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 73kDa |
Gene ID | 79072 |
---|---|
Alias Symbol | FLJ23274, MGC142123, MGC5297 |
Other Names | FAST kinase domain-containing protein 3, FASTKD3 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-FASTKD3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | FASTKD3 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | FASTKD3 |
---|---|
Function | Required for normal mitochondrial respiration (PubMed:20869947). Increases steady-state levels and half-lives of a subset of mature mitochondrial mRNAs MT-ND2, MT-ND3, MT-CYTB, MT-CO2, and MT-ATP8/6. Promotes MT-CO1 mRNA translation and increases mitochondrial complex IV assembly and activity (PubMed:27789713). |
Cellular Location | Mitochondrion |
Tissue Location | Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in liver and thyroid |
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Provided below are standard protocols that you may find useful for product applications.
References
Schmutz J.,et al.Nature 431:268-274(2004).
Sjoeblom T.,et al.Science 314:268-274(2006).
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