C1QL3 Antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
---|---|
Primary Accession | Q5VWW1 |
Other Accession | NP_001010908 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 28kDa |
Gene ID | 389941 |
---|---|
Alias Symbol | C1QL3, CTRP13, |
Other Names | Complement C1q-like protein 3, C1q and tumor necrosis factor-related protein 13, C1q/TNF-related protein 13, C1QL3, CTRP13 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 &mu, l of distilled water. Final Anti-C1QL3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |
Precautions | C1QL3 Antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | C1QL3 |
---|---|
Synonyms | CTRP13 |
Function | May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity). Plays a role in glucose homeostasis. Via AMPK signaling pathway, stimulates glucose uptake in adipocytes, myotubes and hepatocytes and enhances insulin-stimulated glucose uptake. In a hepatoma cell line, reduces the expression of gluconeogenic enzymes G6PC1 and PCK1 and hence decreases de novo glucose production (By similarity). |
Cellular Location | Secreted. |
Tissue Location | Highly expressed in adipose tissue, with expression levels at least 2 orders of magnitude higher than in other tissues, including brain and kidney. |
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Provided below are standard protocols that you may find useful for product applications.
References
Deloukas P.,et al.Nature 429:375-381(2004).
Wei Z.,et al.J. Biol. Chem. 286:15652-15665(2011).
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