CCDC66 Antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | A2RUB6 |
Other Accession | NM_001012506, NP_001012524 |
Reactivity | Human, Horse, Bovine, Dog |
Predicted | Human, Horse, Bovine, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 91kDa |
Gene ID | 285331 |
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Other Names | Coiled-coil domain-containing protein 66, CCDC66 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-CCDC66 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | CCDC66 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CCDC66 (HGNC:27709) |
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Function | Microtubule-binding protein required for ciliogenesis (PubMed:28235840). May function in ciliogenesis by mediating the transport of proteins like BBS4 to the cilium, but also through the organization of the centriolar satellites (PubMed:28235840). Plays a role in retina morphogenesis and/or homeostasis (By similarity). |
Cellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Photoreceptor inner segment. Cell projection, cilium, photoreceptor outer segment. Note=Restricted to the centrosomes and the spindle microtubules during mitosis (PubMed:28235840). Enriched in the inner segment of the photoreceptor (PubMed:19777273). |
Tissue Location | Widely expressed (at protein level) (PubMed:28235840). Expressed in retina, mainly in photoreceptors but also in outer plexiform and ganglion cell layers (at protein level) (PubMed:19777273). |
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