|Other Accession||NM_024898, NP_079174|
|Other Names||DENN domain-containing protein 1C, Connecdenn 3, Protein FAM31C, DENND1C, FAM31C|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-DENND1C antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||DENND1C Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Guanine nucleotide exchange factor (GEF) which may activate RAB8A, RAB13 and RAB35. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.|
|Cellular Location||Cytoplasm, cytosol. Cytoplasmic vesicle, clathrin-coated vesicle|
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Provided below are standard protocols that you may find useful for product applications.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Marat A.L.,et al.J. Biol. Chem. 285:10627-10637(2010).
Yoshimura S.,et al.J. Cell Biol. 191:367-381(2010).
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