|Other Accession||NM_015177, NP_055992|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Other Names||E3 ubiquitin-protein ligase DTX4, 6.3.2.-, Protein deltex-4, Deltex4, RING finger protein 155, DTX4, KIAA0937, RNF155|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-DTX4 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||DTX4 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations (By similarity). Functions as a ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4.|
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Provided below are standard protocols that you may find useful for product applications.
Nagase T.,et al.DNA Res. 6:63-70(1999).
Storck S.,et al.Mol. Cell. Biol. 25:1437-1445(2005).
Cui J.,et al.Nat. Immunol. 13:387-395(2012).
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