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>   home   >   Products   >   Primary Antibodies   >   H2AFB1 Antibody - N-terminal region   

H2AFB1 Antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - H2AFB1 Antibody - N-terminal region AI15618

    Host: Rabbit
    Target Name: H2AFB1
    Sample Tissue: A549 Whole cell lysate
    Antibody Dilution: 1.0μg/mlH2AFB1 is supported by BioGPS gene expression data to be expressed in A549
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P0C5Y9
Other Accession NM_001017990, NP_001017990
Reactivity Human
Predicted Human
Host Rabbit
Clonality Polyclonal
Calculated MW 13kDa
Additional Information
Gene ID 474382
Alias Symbol H2A.Bbd
Other Names Histone H2A-Bbd type 1, H2A Barr body-deficient, H2A.Bbd, H2AFB1
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-H2AFB1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsH2AFB1 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name H2AFB1
Function Atypical histone H2A which can replace conventional H2A in some nucleosomes and is associated with active transcription and mRNA processing. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Nucleosomes containing this histone are less rigid and organize less DNA than canonical nucleosomes in vivo. They are enriched in actively transcribed genes and associate with the elongating form of RNA polymerase. They associate with spliceosome components and are required for mRNA splicing. May participate in spermatogenesis.
Cellular Location Nucleus. Chromosome. Note=Associated with the active X chromosome and with autosomes, while it is absent from the inactive X chromosome and excluded from Barr bodies
Tissue Location Present in mature sperm.
Citations (0)

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Naylor J.A.,et al.Hum. Mol. Genet. 4:1217-1224(1995).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Ross M.T.,et al.Nature 434:325-337(2005).
Bao Y.,et al.EMBO J. 23:3314-3324(2004).
Okuwaki M.,et al.Mol. Cell. Biol. 25:10639-10651(2005).

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$ 293.00
Cat# AI15618
(40 western blots)
Availability: 2-3 days
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