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CCDC176 Antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q8ND07 |
| Other Accession | NM_025057, NP_079333 |
| Reactivity | Human, Mouse, Rat, Pig, Horse, Bovine, Guinea Pig, Dog |
| Predicted | Human, Mouse, Rat, Pig, Horse, Bovine, Guinea Pig, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 58kDa |
| Gene ID | 80127 |
|---|---|
| Other Names | Basal body-orientation factor 1, Coiled-coil domain-containing protein 176, CCDC176, BBOF1, C14orf45 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-CCDC176 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | CCDC176 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | BBOF1 (HGNC:19855) |
|---|---|
| Synonyms | C14orf45, CCDC176 |
| Function | Plays an essential role in sperm motility and male fertility by stabilizing the sperm flagellar axonemal structure. May be required for the stability of ODF2 and MANS1 proteins. Dispensable for the assembly and function of motile cilia. |
| Cellular Location | Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:A0JMY4}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:Q3V079}. Note=Localizes to a polar structure adjacent to the basal body. {ECO:0000250|UniProtKB:A0JMY4} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Heilig R.,et al.Nature 421:601-607(2003).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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