|Other Accession||NM_033626, NP_296375|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Other Names||Coiled-coil domain-containing protein 120, CCDC120|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-CCDC120 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||CCDC120 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Required for neurite growth. Localizes CYTH2 to vesicles to allow its transport along neurites, and subsequent ARF6 activation and neurite growth.|
|Cellular Location||Cytoplasm. Cell projection. Cell projection, growth cone. Endosome. Note=In differentiating neuroblastoma cells, colocalizes with CYTH2 in both neurite shaft and growth cone areas. Partially colocalizes with endosomes along neurites in differentiating neuroblastoma cells|
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Provided below are standard protocols that you may find useful for product applications.
Rolfs A.,et al.Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ross M.T.,et al.Nature 434:325-337(2005).
Matsuoka S.,et al.Science 316:1160-1166(2007).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
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