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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   METRNL Antibody - C-terminal region   

METRNL Antibody - C-terminal region

Rabbit Polyclonal Antibody

  • WB - METRNL Antibody - C-terminal region AI15757

    Host: Rabbit
    Target Name: METRNL
    Sample Tissue: Fetal Liver lysates
    Antibody Dilution: 1.0μg/ml
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q641Q3
Other Accession NM_001004431, NP_001004431
Reactivity Human, Mouse, Rat, Rabbit, Horse, Yeast, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Horse, Yeast, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 29kDa
Additional Information
Gene ID 284207
Other Names Meteorin-like protein, Subfatin, METRNL
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-METRNL antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsMETRNL Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Hormone induced following exercise or cold exposure that promotes energy expenditure. Induced either in the skeletal muscle after exercise or in adipose tissue following cold exposure and is present in the circulation. Able to stimulate energy expenditure associated with the browning of the white fat depots and improves glucose tolerance. Does not promote an increase in a thermogenic gene program via direct action on adipocytes, but acts by stimulating several immune cell subtypes to enter the adipose tissue and activate their prothermogenic actions. Stimulates an eosinophil-dependent increase in IL4 expression and promotes alternative activation of adipose tissue macrophages, which are required for the increased expression of the thermogenic and anti- inflammatory gene programs in fat. Required for some cold-induced thermogenic responses, suggesting a role in metabolic adaptations to cold temperatures (By similarity).
Cellular Location Secreted.
Tissue Location Highly expressed in the skeletal muscle, in subcutaneous adipose tissue, epididymal white adipose tissue depots and heart. Also expressed in brown adipose tissues and kidney.
Research Areas
Citations (0)

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Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Rao R.R.,et al.Cell 157:1279-1291(2014).
Li Z.Y.,et al.CNS Neurosci. Ther. 20:344-354(2014).

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$ 293.00
Cat# AI15757
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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