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NUGGC Antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • WB - NUGGC Antibody - C-terminal region AI15769

    Host: Rabbit
    Target Name: NUGGC
    Sample Tissue: PANC1 Whole cell lysate
    s
    Antibody Dilution: 1.0μg/ml
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q68CJ6
Other Accession NM_001010906NP_001010906
Reactivity Human, Rabbit, Pig, Horse, Bovine, Dog
Predicted Human, Rabbit, Pig, Horse, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 91kDa
Additional Information
Gene ID 389643
Alias Symbol C8orf80, SLIP-GC
Other Names Nuclear GTPase SLIP-GC, 3.6.1.-, Speckled-like pattern in the germinal center, NUGGC, C8orf80
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-NUGGC antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsNUGGC Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NUGGC
Synonyms C8orf80
Function Nuclear GTPase found in germinal center B-cells, where it may inhibit function of the activation-induced cytidine deaminase AICDA (PubMed:19734146). Reduces somatic hypermutation in B-cells which may enhance genome stability (By similarity).
Cellular Location Nucleus speckle
Tissue Location Expressed in germinal center B-cell and in lymphomas derived from germinal center B-cell
Research Areas
Citations (0)

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Background

Plays a role as replication-related GTPase protein in germinal center B-cell.

References

Nusbaum C.,et al.Nature 439:331-335(2006).
Yamada S.,et al.Oncogene 23:5901-5911(2004).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Richter K.,et al.J. Biol. Chem. 284:30652-30661(2009).

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$ 293.00
Cat# AI15769
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