|Other Accession||NM_000204, NP_000195|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Alias Symbol||CFI, IF,|
|Other Names||Complement factor I, 220.127.116.11, C3B/C4B inactivator, Complement factor I heavy chain, Complement factor I light chain, CFI, IF|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 &mu, l of distilled water. Final Anti-CFI antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||CFI Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Responsible for cleaving the alpha-chains of C4b and C3b in the presence of the cofactors C4-binding protein and factor H respectively.|
|Cellular Location||Secreted, extracellular space.|
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Provided below are standard protocols that you may find useful for product applications.
Responsible for cleaving the alpha-chains of C4b and C3b in the presence of the cofactors C4-binding protein and factor H respectively.
Catterall C.F.,et al.Biochem. J. 242:849-856(1987).
Goldberger G.,et al.J. Biol. Chem. 262:10065-10071(1987).
Hillier L.W.,et al.Nature 434:724-731(2005).
Minta J.O.,et al.Gene 208:17-24(1998).
Ullman C.G.,et al.FEBS Lett. 371:199-203(1995).
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