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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   XKR8 Antibody - C-terminal region   

XKR8 Antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • WB - XKR8 Antibody - C-terminal region AI16000

    Host: Rabbit
    Target Name: XKR8
    Sample Tissue: HepG2 Whole cell lysate
    s
    Antibody Dilution: 1.0μg/ml
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q9H6D3
Other Accession NM_018053, NP_060523
Reactivity Human, Rabbit
Predicted Human, Rabbit
Host Rabbit
Clonality Polyclonal
Calculated MW 43kDa
Additional Information
Gene ID 55113
Alias Symbol RP11-460I13.3, XRG8
Other Names XK-related protein 8, hXkr8, XK-related protein 8, processed form, XKR8, XRG8
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 &mu, l of distilled water. Final Anti-XKR8 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
PrecautionsXKR8 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name XKR8
Synonyms XRG8
Function Promotes phosphatidylserine exposure on apoptotic cell surface, possibly by mediating phospholipid scrambling. Phosphatidylserine is a specific marker only present at the surface of apoptotic cells and acts as a specific signal for engulfment. Has no effect on calcium-induced exposure of phosphatidylserine. Activated upon caspase cleavage, suggesting that it does not act prior the onset of apoptosis.
Cellular Location Cell membrane; Multi-pass membrane protein
Research Areas
Citations (0)

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Background

Promotes phosphatidylserine exposure on apoptotic cell surface, possibly by mediating phospholipid scrambling. Phosphatidylserine is a specific marker only present at the surface of apoptotic cells and acts as a specific signal for engulfment. Has no effect on calcium-induced exposure of phosphatidylserine. Activated upon caspase cleavage, suggesting that it does not act prior the onset of apoptosis.

References

Huang C.-H.,et al.Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mayya V.,et al.Sci. Signal. 2:RA46-RA46(2009).
Suzuki J.,et al.Science 341:403-406(2013).

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$ 293.00
Cat# AI16000
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