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IGLC1 Antibody - middle region

Rabbit Polyclonal Antibody

     
  • WB - IGLC1 Antibody - middle region AI16019

    Host: Rabbit
    Target Name: IGLC1
    Sample Tissue: Fetal Liver lysates
    Antibody Dilution: 1.0μg/ml
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P0CG04
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 11kDa
Additional Information
Other Names Ig lambda-1 chain C regions, IGLC1
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 &mu, l of distilled water. Final Anti-IGLC1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
PrecautionsIGLC1 Antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IGLC1 {ECO:0000303|PubMed:11872955, ECO:0000303|Ref.6}
Function Constant region of immunoglobulin light chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins- secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
Cellular Location Secreted. Cell membrane
Research Areas
Citations (0)
citation

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References

Fett J.W.,et al.Biochemistry 13:4102-4114(1974).
Vasicek T.J.,et al.J. Exp. Med. 172:609-620(1990).
Hieter P.A.,et al.Nature 294:536-540(1981).
Edmundson A.B.,et al.Biochemistry 14:3953-3961(1975).
Ely K.R.,et al.J. Mol. Biol. 210:601-615(1989).

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$ 389.00
Cat# AI16019
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