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SMARCAL1 Antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • WB - SMARCAL1 Antibody - N-terminal region AI16065

    Host: Rabbit
    Target Name: SMARCAL1
    Sample Tissue: PANC1 Whole cell lysate
    s
    Antibody Dilution: 1.0μg/ml
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q9NZC9
Other Accession XP_005246689
Reactivity Human
Predicted Human
Host Rabbit
Clonality Polyclonal
Calculated MW 104kDa
Additional Information
Gene ID 50485
Alias Symbol SMARCAL1, HARP,
Other Names SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1, 3.6.4.-, HepA-related protein, hHARP, Sucrose nonfermenting protein 2-like 1, SMARCAL1, HARP
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 &mu, l of distilled water. Final Anti-SMARCAL1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
PrecautionsSMARCAL1 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SMARCAL1
Synonyms HARP
Function ATP-dependent annealing helicase that binds selectively to fork DNA relative to ssDNA or dsDNA and catalyzes the rewinding of the stably unwound DNA. Rewinds single-stranded DNA bubbles that are stably bound by replication protein A (RPA). Acts throughout the genome to reanneal stably unwound DNA, performing the opposite reaction of many enzymes, such as helicases and polymerases, that unwind DNA. May play an important role in DNA damage response by acting at stalled replication forks.
Cellular Location Nucleus. Note=Recruited to damaged DNA regions
Tissue Location Ubiquitously expressed, with high levels in testis.
Citations (0)

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Background

ATP-dependent annealing helicase that binds selectively to fork DNA relative to ssDNA or dsDNA and catalyzes the rewinding of the stably unwound DNA. Rewinds single-stranded DNA bubbles that are stably bound by replication protein A (RPA). Acts throughout the genome to reanneal stably unwound DNA, performing the opposite reaction of many enzymes, such as helicases and polymerases, that unwind DNA. May play an important role in DNA damage response by acting at stalled replication forks.

References

Coleman M.A.,et al.Genomics 65:274-282(2000).
Boerkoel C.F.,et al.Nat. Genet. 30:215-220(2002).
Hillier L.W.,et al.Nature 434:724-731(2005).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Bechtel S.,et al.BMC Genomics 8:399-399(2007).

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$ 293.00
Cat# AI16065
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