|Alias Symbol||SENP8, DEN1, NEDP1, PRSC2, FKSG8,|
|Other Names||Sentrin-specific protease 8, 22.214.171.124, Deneddylase-1, NEDD8-specific protease 1, Protease, cysteine 2, Sentrin/SUMO-specific protease SENP8, SENP8, DEN1, NEDP1, PRSC2|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 &mu, l of distilled water. Final Anti-SENP8 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||SENP8 Antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||DEN1, NEDP1, PRSC2|
|Function||Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53.|
|Tissue Location||Broadly expressed, with highest levels in kidney and pancreas.|
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Provided below are standard protocols that you may find useful for product applications.
Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53.
Mendoza H.M.,et al.J. Biol. Chem. 278:25637-25643(2003).
Gong L.,et al.Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases.
Wang Y.-G.,et al.Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases.
Wu K.,et al.J. Biol. Chem. 278:28882-28891(2003).
Gan-Erdene T.,et al.J. Biol. Chem. 278:28892-28900(2003).
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