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LRCH1 Antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q9Y2L9 |
| Other Accession | NP_055931 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 80kDa |
| Gene ID | 23143 |
|---|---|
| Alias Symbol | LRCH1, CHDC1, KIAA1016, |
| Other Names | Leucine-rich repeat and calponin homology domain-containing protein 1, Calponin homology domain-containing protein 1, Neuronal protein 81, NP81, LRCH1, CHDC1, KIAA1016 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 &mu, l of distilled water. Final Anti-LRCH1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | LRCH1 Antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | LRCH1 |
|---|---|
| Synonyms | CHDC1, KIAA1016 |
| Function | Acts as a negative regulator of GTPase CDC42 by sequestering CDC42-guanine exchange factor DOCK8. Probably by preventing CDC42 activation, negatively regulates CD4(+) T-cell migration. |
| Cellular Location | Cytoplasm. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Guo J.H.,et al.Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases.
Nagase T.,et al.DNA Res. 6:63-70(1999).
Nakajima D.,et al.DNA Res. 9:99-106(2002).
Dunham A.,et al.Nature 428:522-528(2004).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
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