|Alias Symbol||REV1, REV1L,|
|Other Names||DNA repair protein REV1, 2.7.7.-, Alpha integrin-binding protein 80, AIBP80, Rev1-like terminal deoxycytidyl transferase, REV1, REV1L|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 &mu, l of distilled water. Final Anti-REV1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||REV1 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.|
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Provided below are standard protocols that you may find useful for product applications.
Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
Lin W.,et al.Nucleic Acids Res. 27:4468-4475(1999).
Gibbs P.E.M.,et al.Proc. Natl. Acad. Sci. U.S.A. 97:4186-4191(2000).
Masuda Y.,et al.J. Biol. Chem. 276:15051-15058(2001).
Murakumo Y.,et al.J. Biol. Chem. 276:35644-35651(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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