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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   BMPR1A Antibody - N-terminal region   

BMPR1A Antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • WB - BMPR1A Antibody - N-terminal region AI16096

    Host: Rabbit
    Target Name: BMPR1A
    Sample Tissue: Jurkat Whole Cell lysates
    Antibody Dilution: 1.0μg/ml
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P36894
Other Accession XP_005270121
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 58kDa
Additional Information
Gene ID 657
Alias Symbol BMPR1A, ACVRLK3, ALK3,
Other Names Bone morphogenetic protein receptor type-1A, BMP type-1A receptor, BMPR-1A, 2.7.11.30, Activin receptor-like kinase 3, ALK-3, Serine/threonine-protein kinase receptor R5, SKR5, CD292, BMPR1A, ACVRLK3, ALK3
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 &mu, l of distilled water. Final Anti-BMPR1A antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
PrecautionsBMPR1A Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BMPR1A
Synonyms ACVRLK3, ALK3
Function On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Highly expressed in skeletal muscle.
Research Areas
Citations (0)

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Background

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP-2 and BMP-4.

References

ten Dijke P.,et al.Oncogene 8:2879-2887(1993).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mahlawat P.,et al.Biochemistry 51:6328-6341(2012).
Kirsch T.,et al.Nat. Struct. Biol. 7:492-496(2000).
Howe J.R.,et al.Nat. Genet. 28:184-187(2001).

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$ 293.00
Cat# AI16096
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