|Other Names||Lysosomal thioesterase PPT2, PPT-2, 3.1.2.-, S-thioesterase G14, PPT2|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 &mu, l of distilled water. Final Anti-PPT2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||PPT2 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Removes thioester-linked fatty acyl groups from various substrates including S-palmitoyl-CoA. Has the highest S- thioesterase activity for the acyl groups palmitic and myristic acid followed by other short- and long-chain acyl substrates. However, because of structural constraints, is unable to remove palmitate from peptides or proteins.|
|Tissue Location||Broadly expressed, with highest levels in skeletal muscle.|
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Provided below are standard protocols that you may find useful for product applications.
Removes thioester-linked fatty acyl groups from various substrates including S-palmitoyl-CoA. Has the highest S- thioesterase activity for the acyl groups palmitic and myristic acid followed by other short- and long-chain acyl substrates. However, because of structural constraints, is unable to remove palmitate from peptides or proteins.
Soyombo A.A.,et al.J. Biol. Chem. 272:27456-27463(1997).
Aguado B.,et al.Biochem. J. 341:679-689(1999).
Wiemann S.,et al.Genome Res. 11:422-435(2001).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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