|Other Names||Chloride intracellular channel protein 3, CLIC3|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 &mu, l of distilled water. Final Anti-CLIC3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||CLIC3 Antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Can insert into membranes and form chloride ion channels. May participate in cellular growth control.|
|Cellular Location||Nucleus. Membrane; Single-pass membrane protein. Cytoplasm. Note=Predominantly nuclear. Some protein was found in the cytoplasm. Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain (By similarity).|
|Tissue Location||Detected in placenta (at protein level). Widely expressed. High expression is found in placenta followed by lung and heart. Low expression in skeletal muscle, kidney and pancreas.|
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Provided below are standard protocols that you may find useful for product applications.
Can insert into membranes and form chloride ion channels. May participate in cellular growth control.
Humphray S.J.,et al.Nature 429:369-374(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Qian Z.,et al.J. Biol. Chem. 274:1621-1627(1999).
Money T.T.,et al.Placenta 28:429-436(2007).
Littler D.R.,et al.Proteins 78:1594-1600(2010).
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