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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   TNFRSF10C antibody - N-terminal region   

TNFRSF10C antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • WB - TNFRSF10C antibody - N-terminal region AI16175

    WB Suggested Anti-TNFRSF10C Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:62500
    Positive Control: Human Stomach
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession O14798
Other Accession NM_003841, NP_003832
Reactivity Human
Predicted Human
Host Rabbit
Clonality Polyclonal
Calculated MW 25kDa
Additional Information
Gene ID 8794
Alias Symbol CD263, DCR1, LIT, MGC149501, MGC149502, TRAILR3, TRID, TRAIL-R3, DCR1-TNFR
Other Names Tumor necrosis factor receptor superfamily member 10C, Antagonist decoy receptor for TRAIL/Apo-2L, Decoy TRAIL receptor without death domain, Decoy receptor 1, DcR1, Lymphocyte inhibitor of TRAIL, TNF-related apoptosis-inducing ligand receptor 3, TRAIL receptor 3, TRAIL-R3, TRAIL receptor without an intracellular domain, CD263, TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-TNFRSF10C antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsTNFRSF10C antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TNFRSF10C
Synonyms DCR1, LIT, TRAILR3, TRID
Function Receptor for the cytotoxic ligand TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.
Cellular Location Cell membrane; Lipid-anchor, GPI-anchor.
Tissue Location Higher expression in normal tissues than in tumor cell lines. Highly expressed in peripheral blood lymphocytes, spleen, skeletal muscle, placenta, lung and heart
Research Areas
Citations (0)

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Background

Receptor for the cytotoxic ligand TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.

References

MacFarlane M.,et al.J. Biol. Chem. 272:25417-25420(1997).
Degli-Esposti M.A.,et al.J. Exp. Med. 186:1165-1170(1997).
Pan G.,et al.Science 277:815-818(1997).
Sheridan J.P.,et al.Science 277:818-821(1997).
Schneider P.,et al.FEBS Lett. 416:329-334(1997).

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$ 293.00
Cat# AI16175
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