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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   RGS9 antibody - N-terminal region   

RGS9 antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • IHC - RGS9 antibody - N-terminal region AI16193
    Human Liver
  • WB - RGS9 antibody - N-terminal region AI16193

    WB Suggested Anti-RGS9 Antibody Titration: 2.0μg/ml
    Positive Control: HepG2 cell lysate
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC
Primary Accession O75916
Other Accession NM_003835, NP_003826
Reactivity Human, Mouse, Rat, Rabbit, Horse, Bovine, Dog
Predicted Human, Mouse, Rat, Rabbit, Horse, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 49kDa
Additional Information
Gene ID 8787
Alias Symbol PERRS, RGS9L
Other Names Regulator of G-protein signaling 9, RGS9, RGS9
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 100 ul of distilled water. Final anti-RGS9 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsRGS9 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RGS9
Function Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(t)-alpha. Involved in phototransduction; key element in the recovery phase of visual transduction (By similarity).
Cellular Location Isoform 3: Membrane; Peripheral membrane protein. Note=Isoform 3 is targeted to the membrane via its interaction with RGS9BP.
Tissue Location Highly expressed in the caudate and putamen, lower levels found in the hypothalamus and nucleus accumbens and very low levels in cerebellum. Not expressed in globus pallidus or cingulate cortex. Isoform 2 is expressed predominantly in pineal gland and retina. Isoform 3 is expressed in retina (abundant in photoreceptors)
Research Areas
Citations (0)

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Background

Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(t)-alpha. Involved in phototransduction; key element in the recovery phase of visual transduction (By similarity).

References

Granneman J.G.,et al.Mol. Pharmacol. 54:687-694(1998).
Zhang K.,et al.Gene 240:23-34(1999).
Puhl H.L. III,et al.Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).

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$ 232.00
Cat# AI16193
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