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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   GABRP antibody - N-terminal region   

GABRP antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • WB - GABRP antibody - N-terminal region AI16206

    WB Suggested Anti-GABRP Antibody Titration: 1.25 μg/ml
    Positive Control: HepG2/Jurkat
  • WB - GABRP antibody - N-terminal region AI16206

    Host: Rabbit
    Target Name:GABRP
    Sample Tissue:Jurkat
    Lane A: Primary Antibody
    Lane B: Primary Antibody + Blocking Peptide
    Primary Antibody
    Concentration:1.0μg/ml
    Peptide Concentration: 1.0μg/ml
    Lysate Quantity: 25ug/lane Gel
    Concentration: 12%
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession O00591
Other Accession NM_014211, NP_055026
Reactivity Human, Mouse, Rat, Rabbit, Horse, Dog
Predicted Human, Mouse, Rat, Rabbit, Horse, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 51kDa
Additional Information
Gene ID 2568
Other Names Gamma-aminobutyric acid receptor subunit pi, GABA(A) receptor subunit pi, GABRP
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 100 ul of distilled water. Final anti-GABRP antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsGABRP antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GABRP
Function GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. In the uterus, the function of the receptor appears to be related to tissue contractility. The binding of this pI subunit with other GABA(A) receptor subunits alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone.
Cellular Location Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein
Tissue Location Most abundant in the uterus, also expressed in lung, thymus and prostate
Research Areas
Citations (0)

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Background

GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. In the uterus, the function of the receptor appears to be related to tissue contractility. The binding of this pI subunit with other GABA(A) receptor subunits alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone.

References

Hedblom E.,et al.J. Biol. Chem. 272:15346-15350(1997).
Johnson E.K.,et al.Submitted (JUN-1997) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Sjoeblom T.,et al.Science 314:268-274(2006).

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$ 232.00
Cat# AI16206
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