HTR7 antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
---|---|
Primary Accession | P34969 |
Other Accession | NM_019859, NP_062873 |
Reactivity | Human, Mouse, Rat, Pig, Horse, Dog |
Predicted | Human, Mouse, Rat, Pig, Horse, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 54kDa |
Gene ID | 3363 |
---|---|
Alias Symbol | 5-HT7 |
Other Names | 5-hydroxytryptamine receptor 7, 5-HT-7, 5-HT7, 5-HT-X, Serotonin receptor 7, HTR7 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-HTR7 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | HTR7 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | HTR7 |
---|---|
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. |
Cellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Location | Isoform A is the predominant isoform in spleen, caudate and hippocampus. Isoform B is expressed at lower levels Isoform D is a minor isoform in terms of expression |
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Provided below are standard protocols that you may find useful for product applications.
Background
This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.
References
Heidmann D.E.A.,et al.J. Neurochem. 68:1372-1381(1997).
Bard J.A.,et al.J. Biol. Chem. 268:23422-23426(1993).
King M.M.,et al.Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Goshima N.,et al.Nat. Methods 5:1011-1017(2008).
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