|Other Accession||NM_004603, NP_004594|
|Reactivity||Human, Mouse, Rat, Pig, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Pig, Bovine, Guinea Pig, Dog|
|Alias Symbol||HPC-1, STX1, p35-1, P35-1, SYN1A|
|Other Names||Syntaxin-1A, Neuron-specific antigen HPC-1, STX1A, STX1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-STX1A antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||STX1A antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Potentially involved in docking of synaptic vesicles at presynaptic active zones. May play a critical role in neurotransmitter exocytosis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.|
|Cellular Location||Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein. Cell junction, synapse, synaptosome|
|Tissue Location||Isoform 1 is highly expressed in embryonic spinal chord and ganglia and in adult cerebellum and cerebral cortex. Isoform 2 is expressed in heart, liver, fat, skeletal muscle, kidney and brain.|
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Potentially involved in docking of synaptic vesicles at presynaptic active zones. May play a critical role in neurotransmitter exocytosis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.
Zhang R.-D.,et al.Gene 159:293-294(1995).
Osborne L.R.,et al.Am. J. Hum. Genet. 61:449-452(1997).
Wu Y.-Q.,et al.Am. J. Med. Genet. 109:121-124(2002).
Jagadish M.N.,et al.Biochem. J. 321:151-156(1997).
Nakayama T.,et al.Genomics 42:173-176(1997).
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