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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   STX1A antibody - N-terminal region   

STX1A antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • WB - STX1A antibody - N-terminal region AI16216

    WB Suggested Anti-STX1A Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:62500
    Positive Control: 721_B cell lysate
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q16623
Other Accession NM_004603, NP_004594
Reactivity Human, Mouse, Rat, Pig, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Pig, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 33kDa
Additional Information
Gene ID 6804
Alias Symbol HPC-1, STX1, p35-1, P35-1, SYN1A
Other Names Syntaxin-1A, Neuron-specific antigen HPC-1, STX1A, STX1
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-STX1A antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsSTX1A antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name STX1A
Synonyms STX1
Function Plays a role in hormone and neurotransmitter exocytosis (By similarity). Potentially involved in docking of synaptic vesicles at presynaptic active zones. May mediate Ca(2+)- regulation of exocytosis acrosomal reaction in sperm.
Cellular Location Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein. Cell junction, synapse, synaptosome. Cell membrane {ECO:0000250|UniProtKB:P32851}. Note=Colocalizes with KCNB1 at the cell membrane. {ECO:0000250|UniProtKB:P32851}
Tissue Location Isoform 1 is highly expressed in embryonic spinal chord and ganglia and in adult cerebellum and cerebral cortex. Isoform 2 is expressed in heart, liver, fat, skeletal muscle, kidney and brain.
Research Areas
Citations (0)

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Background

Potentially involved in docking of synaptic vesicles at presynaptic active zones. May play a critical role in neurotransmitter exocytosis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.

References

Zhang R.-D.,et al.Gene 159:293-294(1995).
Osborne L.R.,et al.Am. J. Hum. Genet. 61:449-452(1997).
Wu Y.-Q.,et al.Am. J. Med. Genet. 109:121-124(2002).
Jagadish M.N.,et al.Biochem. J. 321:151-156(1997).
Nakayama T.,et al.Genomics 42:173-176(1997).

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$ 293.00
Cat# AI16216
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