|Other Accession||NM_005604, NP_005595|
|Reactivity||Human, Rat, Pig, Bovine|
|Predicted||Human, Rat, Pig, Bovine|
|Alias Symbol||BRN2, OCT7, OTF7, OTF-7, POUF3, brn-2, oct-7|
|Other Names||POU domain, class 3, transcription factor 2, Brain-specific homeobox/POU domain protein 2, Brain-2, Brn-2, Nervous system-specific octamer-binding transcription factor N-Oct-3, Octamer-binding protein 7, Oct-7, Octamer-binding transcription factor 7, OTF-7, POU3F2, BRN2, OCT7, OTF7|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-POU3F2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||POU3F2 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||BRN2, OCT7, OTF7|
|Function||Transcription factor that binds preferentially to the recognition sequence which consists of two distinct half-sites, ('GCAT') and ('TAAT'), separated by a nonconserved spacer region of 0, 2, or 3 nucleotides. Positively regulates the genes under the control of corticotropin-releasing hormone (CRH) and CRH II promoters (By similarity).|
|Tissue Location||Expressed specifically in the neuroectodermal cell lineage|
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Provided below are standard protocols that you may find useful for product applications.
Transcription factor that binds preferentially to the recognition sequence which consists of two distinct half-sites, ('GCAT') and ('TAAT'), separated by a nonconserved spacer region of 0, 2, or 3 nucleotides. Positively regulates the genes under the control of corticotropin-releasing hormone (CRH) and CRH II promoters (By similarity).
Schreiber E.,et al.Nucleic Acids Res. 21:253-258(1993).
Angus J.,et al.Oncogene 11:691-700(1995).
Mungall A.J.,et al.Nature 425:805-811(2003).
He X.,et al.Nature 340:35-42(1989).
Waragai M.,et al.Hum. Mol. Genet. 8:977-987(1999).
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