|Application ||WB, IHC|
|Other Accession||NM_005513, NP_005504|
|Reactivity||Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Mouse, Rat, Rabbit, Chicken, Horse, Bovine, Guinea Pig, Dog|
|Alias Symbol||FE, TF2E1, TFIIE-A|
|Other Names||General transcription factor IIE subunit 1, General transcription factor IIE 56 kDa subunit, Transcription initiation factor IIE subunit alpha, TFIIE-alpha, GTF2E1, TF2E1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-GTF2E1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||GTF2E1 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.|
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Provided below are standard protocols that you may find useful for product applications.
Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
Peterson M.G.,et al.Nature 354:369-373(1991).
Ohkuma Y.,et al.Nature 354:398-401(1991).
Bienvenut W.V.,et al.Submitted (JAN-2010) to UniProtKB.
Hisatake K.,et al.Proc. Natl. Acad. Sci. U.S.A. 92:8195-8199(1995).
Di Valentin E.,et al.Biol. Chem. 386:255-267(2005).
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