|Application ||WB, IHC|
|Other Accession||NM_005513, NP_005504|
|Reactivity||Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Mouse, Rat, Rabbit, Chicken, Horse, Bovine, Guinea Pig, Dog|
|Alias Symbol||FE, TF2E1, TFIIE-A|
|Other Names||General transcription factor IIE subunit 1, General transcription factor IIE 56 kDa subunit, Transcription initiation factor IIE subunit alpha, TFIIE-alpha, GTF2E1, TF2E1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-GTF2E1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||GTF2E1 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
Peterson M.G.,et al.Nature 354:369-373(1991).
Ohkuma Y.,et al.Nature 354:398-401(1991).
Bienvenut W.V.,et al.Submitted (JAN-2010) to UniProtKB.
Hisatake K.,et al.Proc. Natl. Acad. Sci. U.S.A. 92:8195-8199(1995).
Di Valentin E.,et al.Biol. Chem. 386:255-267(2005).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.