Register or Login
Catalog #
  • All
  • Uniprot Id
  • Catalog #
>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Acyl thioesterase 1 Antibody   

Acyl thioesterase 1 Antibody

Rabbit Monoclonal

Produced using Abcam's RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487
United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanKoreaLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamOthers
Ordering Information
Catalog # SizeAvailability Price  
AJ1014b 100µl 2-3 days $ 337.00 Add to cart
  • Specification
  • Citations : 0
  • Reviews
  • Protocols
  • Background

Acyl thioesterase 1 Antibody - Product Information

  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • ICC=Immunocytochemistry
  • CHIP=Chromatin Immunoprecipitation
  • IHCF=Immunohistochemistry (Frozen Sections)
  • FA=Fluorescence Assay
  • IHCP=Immunohistochemistry (Paraffin-embedded Sections)
  • IC=Immunochemistry
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary AccessionO75608
ReactivityHuman, Mouse, Rat
Clone NamesEPR3667
Calculated MW24670 Da Da
Gene ID 10434
Other Names
Acyl-protein thioesterase 1, APT-1, hAPT1, 312-, Lysophospholipase 1, Lysophospholipase I, LPL-I, LysoPLA I, LYPLA1, APT1, LPL1
A synthetic peptide corresponding to residues in human Acyl protein thioesterase 1 was used as an immunogen.
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Acyl thioesterase 1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Acyl thioesterase 1 Antibody - Protein Information

Synonyms APT1, LPL1
Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity toward KCNMA1. Has low lysophospholipase activity.
Cellular Location

Acyl thioesterase 1 Antibody - Related Products

AP19062c: LYPLA1 Antibody (Center)

BP19062c: LYPLA1 Antibody (Center) Blocking Peptide

AJ1014a: Acyl thioesterase 1 Antibody

Acyl thioesterase 1 Antibody - Research Areas

Application Data

  • WB - Acyl thioesterase 1 Antibody AJ1014b

    A. Western blot analysis on (A) fetal liver, (B) fetal heart, (C) human spleen, (D) mouse heart, (E) mouse kidney, (F) mouse spleen and (G) rat kidney lysates using anti-Acyl protein thioesterase 1 RabMAb (Cat. #AJ1014b).

  • IHC - Acyl thioesterase 1 Antibody AJ1014b

    B. Immunohistochemical analysis of paraffin-embedded human brain using anti-Acyl protein thioesterase 1 RabMAb (Cat. #AJ1014b).

  • WB - Acyl thioesterase 1 Antibody AJ1014b
  • IHC - Acyl thioesterase 1 Antibody AJ1014b

ELITE™ Custom Antibody Services

Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the
"Submit Review" button and provide the requested information. Our staff will examine and post your
review and contact you if needed.

If you have any additional inquiries please email technical services at

Thank you for your support.


Provided below are standard protocols that you may find useful for product applications.


Acyl-protein thioesterase 1 (APT1, Lysophospholipase 1) is a member of a family of critical enzymes, lysophospholipases, that act on biological membranes to regulate the multifunctional lysophospholipids (1). APT1 hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS (2). The role of APT1 in regulating lysophospholipids is important because increased levels of lysophospholipids are detected in a variety of diseases, including atherosclerosis and hyperlipidemia (1). Regulated expression of acyl-protein thioesterase by PKC has been suggested to have important implications for signal transduction processes (3).


1. Wang A, et al. Biochim Biophys Acta. 1437(2):157-69, 1999 2. The UniProt Consortium, The Universal Protein Resource (UniProt). Nucleic Acids Res., 36:D190-D195 (2008) 3. Wang A, et al. Biochim Biophys Acta. 1484(2-3):207-14, 2000