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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Aldolase B Antibody   

Aldolase B Antibody

Rabbit Monoclonal Antibody

  • WB - Aldolase B Antibody AJ1024a
    A. Western blot analysis on fetal kidney lysate using anti-Aldolase B RabMAb (Cat. #AJ1024a), dilution 1:1000.
  • IHC - Aldolase B Antibody AJ1024a
    B. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Adolase B RabMAb (Cat. #AJ1024a).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P05062
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Monoclonal
Clone Names EPR3138Y
Calculated MW 39473 Da
Gene ID 229
Other Names Fructose-bisphosphate aldolase B, Liver-type aldolase, ALDOB, ALDB
Target/Specificity A synthetic peptide corresponding to residues in human Aldolase B was used as an immunogen.
Dilution WB~~1:500~1000
Format 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsAldolase B Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms ALDB
Cellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite
Research Areas
Citations (0)

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Aldolase B is one of three known aldolase isoenzymes, and is found in kidney and small adult intestine where it is associated with aldolases A or C. Aldolase B catalyzes the reversible cleavage of fructose 1-phosphate into dihydroxyacetone phosphate and glyceraldehyde. It is involved in both glycolytic and gluconeogenic pathways, where its quaternary structure is critical for maintaining its full catalytic function. Hereditary fructose intolerance (HFI), a potentially fatal human autosomal recessive disease of carbohydrate metabolism, results with Aldolase B deficiency. Partially active Aldolase B, however, has been reported in an HFI individuals, which supports the hypothesis that adequate gluconeogenesis/glycolysis is maintained in HFI patients by the presence of partially active enzymes (1-4).


1. Rellos P, et al. J Biol Chem. 275(2):1145-51, 2000
2. Cross NC, et al. Cell. 53(6):881-5, 1988
3. Brooks CC, et al. FASEB J. 8(1):107-13, 1994
4. Gregori C, et al. J Biol Chem, 273(39):25237-25243, 1998

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Cat# AJ1024a
(40 western blots)
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