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Apolipoprotein M Antibody

Rabbit Monoclonal Antibody

  • WB - Apolipoprotein M Antibody AJ1055a
    Western blot analysis on (A) human plasma and (B) HDL cell lysates using anti-Apolipoprotein M RabMAb (Cat. #AJ1055a).
  • IHC - Apolipoprotein M Antibody AJ1055a
    Immunohistochemical analysis of paraffin-embedded human liver tissue using anti- ApoM RabMAb (Cat. #AJ1055a).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O95445
Reactivity Human
Host Rabbit
Clonality Monoclonal
Clone Names EPR2904
Calculated MW 21253 Da
Gene ID 55937
Other Names Apolipoprotein M, Apo-M, ApoM, Protein G3a, APOM, G3A, NG20
Target/Specificity A synthetic peptide corresponding to residues in human Apolipoprotein M was used as an immunogen.
Dilution WB~~1:2000~10000
Format 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsApolipoprotein M Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms G3A, NG20
Function Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid.
Cellular Location Secreted Note=Present in high density lipoprotein (HDL) and to a lesser extent in triglyceride-rich lipoproteins (TGRLP) and low density lipoproteins (LDL)
Tissue Location Plasma protein. Expressed in liver and kidney.
Research Areas
Citations (0)

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Apolipoprotein M (ApoM) is a novel apolipoprotein mainly present in high-density lipoprotein (HDL) (1,2). It belongs to the lipocalin protein superfamily and may bind a small but so far unknown lipophilic ligand. It is secreted without cleavage of its hydrophobic signal peptide, which probably anchors ApoM in the phospholipid moiety of plasma lipoproteins. Recent studies suggest that ApoM may affect HDL metabolism and have anti-atherogenic functions (2), including possible mechanisms of increased formation of pre-ss HDL, enhanced cholesterol mobilization from foam cells, and increased antioxidant properties (1). In addition to hepatocytes, ApoM is highly expressed in kidney proximal tubule cells (2).


1. Dahlb鋍k B, et al. Cell Mol Life Sci. 66(4):559-64, 2009 2. Christoffersen C, et al. Scand J Clin Lab Invest. 66(7):631-7, 2006

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Cat# AJ1055a
(40 western blots)
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