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Apolipoprotein-F (ApoF) Antibody

Rabbit Monoclonal Antibody

  • WB - Apolipoprotein-F (ApoF) Antibody AJ1058a
    A.Western blot analysis on (A) HDL and (B) human plasma lysates using anti-Apolipoprotein F (apo F) RabMAb (Cat. #AJ1058a), dilution 1:2000.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13790
Reactivity Human, Mouse
Host Rabbit
Clonality Monoclonal
Clone Names EPR2908
Calculated MW 35399 Da
Gene ID 319
Other Names Apolipoprotein F, Apo-F, Lipid transfer inhibitor protein, LTIP, APOF
Target/Specificity A synthetic peptide corresponding to residues in human Apolipoprotein F (apo F) was used as an immunogen.
Dilution WB~~1:1000~2000
Format 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsApolipoprotein-F (ApoF) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Minor apolipoprotein that associates with LDL. Inhibits cholesteryl ester transfer protein (CETP) activity and appears to be an important regulator of cholesterol transport. Also associates to a lesser degree with VLDL, Apo-AI and Apo-AII.
Cellular Location Secreted.
Tissue Location Expressed by the liver and secreted in plasma.
Research Areas
Citations (0)

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Apolipoprotein F (Apo F), also known as lipid transfer inhibitor protein (LTIP) based on its ability to inhibit lipid transfer between lipoproteins, is a protein component of several lipoprotein classes and a physiologic regulator of cholesteryl ester transfer protein (CETP) function (1, 2). Apo F activity was reported to be localized to LDL, consistent with its greater inhibitory activity on this lipoprotein. Apo F activity is controlled by its reversible incorporation into an inactive complex which provides for short-term fine-tuning of lipoprotein remodeling mediated by CETP (1). ApoF overexpression reduces HDL cholesterol levels by increasing clearance of HDL-CE. ApoF may be an important determinant of HDL metabolism and reverse cholesterol transport (2).


1. He Y, et al. J Lipid Res. 49(7):1529-37, 2008
2. Lagor WR, et al. Arterioscler Thromb Vasc Biol. 29(1):40-6, 2008

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Cat# AJ1058a
(40 western blots)
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