Register or Login
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Aquaporin-5 Antibody   

Aquaporin-5 Antibody

Rabbit Monoclonal Antibody

  • WB - Aquaporin-5 Antibody AJ1059a
    Western blot analysis on (A) fetal lung and (B) SW480 cell lysates using anti-Aquaporin 5 RabMAb (Cat. #AJ1059a).
  • IHC - Aquaporin-5 Antibody AJ1059a
    Immunohistochemical analysis of paraffin-embedded human lung tissue using anti-Aquaporin 5 RabMAb (Cat. #AJ1059a).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P55064
Reactivity Human
Host Rabbit
Clonality Monoclonal
Clone Names EPR3747
Calculated MW 28292 Da
Gene ID 362
Other Names Aquaporin-5, AQP-5, AQP5
Target/Specificity A synthetic peptide corresponding to residues in human Aquaporin 5 was used as an immunogen.
Dilution WB~~1:1000~10000
Format 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsAquaporin-5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AQP5
Function Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions. Required for TRPV4 activation by hypotonicity (PubMed:16571723). Together with TRPV4, controls regulatory volume decrease in salivary epithelial cells (PubMed:16571723).
Cellular Location Apical cell membrane {ECO:0000250|UniProtKB:Q9WTY4}; Multi-pass membrane protein
Research Areas
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to, and receive a free "I Love Antibodies" mug.


Aquaporin 5 is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions (1). It is expressed in epithelia of lung, cornea, and various secretory glands; sites where extracellular osmolality is known to fluctuate (2). Expression of Aquaporin 5 may have pathophysiological implications attributed to a dysfunctional water regulation by Aquaporin 5such as endolymphatic hydrops (i.e. in Meniere's disease) or sensorineural hearing loss (i.e. in Sj鰃ren's syndrome) (3). Up-regulation of Aquaporin 5 may be involved in differentiation of human gastric cancer cells (4).


1. Da Silva N., et al. Biol Reprod. 74(2):427-38, 2006 2. NCBI Reference Sequence (RefSeq): a curated non- redundant sequence database of genomes, transcripts and proteins Pruitt KD, Tatusova, T, Maglott DR Nucleic Acids Res 2007 Jan 1;35(Database issue):D61-5 3. Sidhaye VK, et al. Proc Natl Acad Sci U S A. 103(12):4747-52, 2006 4. Hirt B, et al. The subcellular distribution of aquaporin 5 in the cochlea reveals a water shunt at the perilymph- endolymph barrier, Neuroscience, 2009 5. Watanabe T, et al. J Physiol Sci. 59(2):113-22, 2009

Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at

Cat# AJ1059a
Alternative Products:

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaCentral AmericaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSouth KoreaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamWorldwideOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609
USA Headquarters
(888) 735-7227 / (858) 622-0099 or (858) 875-1900

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Crown Flash21-30% Off
Terms & Conditions