Register or Login
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   Bcl-2 A1/Bfl1 Antibody (N-term)   

Bcl-2 A1/Bfl1 Antibody (N-term)

Rabbit Monoclonal Antibody

  • WB - Bcl-2 A1/Bfl1 Antibody (N-term) AJ1081a
    A. Western blot analysis on Raji cell lysate using anti- Bcl-2-related protein A1 (N-term) RabMAb (Cat. #AJ1081a), dilution 1:500.
  • IHC - Bcl-2 A1/Bfl1 Antibody (N-term) AJ1081a
    B. Immunohistochemical analysis of paraffin-embedded human adenocarcinoma using anti-Bcl-2-related protein A1 (N-term)RabMAb (Cat. #AJ1081a).
  • IF - Bcl-2 A1/Bfl1 Antibody (N-term) AJ1081a
    C. Immunofluorescent staining of HeLa cells using anti-Bcl-2-related protein A1 (N-term) RabMAb (Cat. #AJ1081a).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q16548
Reactivity Human, Mouse
Host Rabbit
Clonality Monoclonal
Clone Names EP517Y
Calculated MW 20132 Da
Gene ID 597
Other Names Bcl-2-related protein A1, Bcl-2-like protein 5, Bcl2-L-5, Hemopoietic-specific early response protein, Protein BFL-1, Protein GRS, BCL2A1, BCL2L5, BFL1, GRS, HBPA1
Target/Specificity A synthetic peptide corresponding to residues in the N-term of human Bcl-2 related protein A1 was used as immunogen.
Dilution WB~~1:5000~10000
Format 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsBcl-2 A1/Bfl1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BCL2A1
Synonyms BCL2L5, BFL1, GRS, HBPA1
Function Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection (By similarity). Can inhibit apoptosis induced by serum starvation in the mammary epithelial cell line HC11 (By similarity).
Cellular Location Cytoplasm.
Tissue Location Seems to be restricted to the hematopoietic compartment. Expressed in peripheral blood, spleen, and bone marrow, at moderate levels in lung, small intestine and testis, at a minimal levels in other tissues. Also found in vascular smooth muscle cells and hematopoietic malignancies
Research Areas
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to, and receive a free "I Love Antibodies" mug.


Bcl-2 related protein A1; also known as Bcl2A1 and Bfl1, is an anti-apoptotic Bcl-2 family member preferentially expressed in hematopoietic and endothelial cells (1). Bfl1 is involved in a variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. Expression of Bfl1 is stimulated by NF-kB in response to inflammatory stimuli and up-regulated by TNF-alpha, IL1-beta, IGF1, GMC-SF, CD40 and phorbol ester (2-3). Bfl1 has also been shown to reduce the release of pro-apoptotic cytochrome c from mitochondria, block caspase activation and suppress apoptosis induced by p53 (4-5).


1. Lin, E. Y.; Orlofsky, A.; Berger, M. S.; Prystowsky, M. B.: J. Immun. 151: 1979-1988, 1993.
2. Lee, H. H., Dadgostar, H., Cheng, Q., Shu, J., and Cheng, G. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 9136-9141
3. Zong, W.-X., Edelstein, L. C., Chen, C., Bash, J., and Gelinas, C. (1999) Genes Dev. 13, 382-387
4. D'Sa-Eipper, C.; Subramanian, T.; Chinnadurai, G. : Cancer Res. 56: 3879-3882, 1996.
5. Arlette B. Werner, Evert de Vries, Stephen W. G. Tait, Ilja Bontjer, and Jannie Borst; J. Biol. Chem., Vol. 277, Issue 25, 22781-22788, June 21, 2002

Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at

Cat# AJ1081a
Alternative Products:

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaCentral AmericaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSouth KoreaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamWorldwideOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609
USA Headquarters
(888) 735-7227 / (858) 622-0099 or (858) 875-1900

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
“Crown Flash”  50 % off on 2,500+ Crown Antibodies. PromoCode:<span class=text-red> FLASH50
Terms & Conditions