- Antibodies
- New
- Biological Process >
- Cellular Compartment >
- Disease >
- Molecular Function >
- Pathway Biocarta >
- Pathway KEGG >
- Pathway Panther >
- Tissue >
- Tag
- Peptides
- Biological Process >
- Cellular Compartment >
- Disease >
- Molecular Function >
- Pathway Biocarta >
- Pathway KEGG >
- Pathway Panther >
- Tissue >
- Amino Acids
- Tag
- Biological Process >
- Proteins
- RNAi
- FL cDNA Clones
- Cell/Tissues/Lysates
Beta-Tubulin AntibodyRabbit Polyclonal IgG Affinity Purified
| Country | United States
Ordering Information
Australia Austria Belgium Brazil Bulgaria Canada China Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland India Indonesia Ireland Israel Italy Japan Korea Latvia Lithuania Luxembourg Macedonia Malaysia Malta Netherlands Norway Pakistan Poland Portugal Romania Serbia Singapore Slovakia Slovenia Spain Sweden Switzerland Taiwan Turkey United Kingdom United States Vietnam Others 
|
|||
|---|---|---|---|---|
| Catalog # | Size | Availability | Price | |
| AJ1097a | 100ul 400 ul | 2-3 days | $ 315.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
Beta-Tubulin Antibody - Product info | |
| Application | WB, IF, IHC
|
| Primary Accession | P07437 |
| Reactivity | Human, Mouse, Rat |
| Clone Names | Polyclonal |
| Calculated MW | 49671 Da |
| Gene ID 203068 | |
| Other Names TUBB, TUBB5, Tubulin beta chain, Tubulin beta-5 chain | |
| Target/Specificity A synthetic peptide corresponding to residues near the C-term of human β-Tubulin was used as immunogen. | |
| Dilution WB~~1:1000~5000 IHC~~1:100~1:250 | |
| Format 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions Beta-Tubulin Antibody is for research use only and not for use in diagnostic or therapeutic procedures. | |
Beta-Tubulin Antibody - Protein Information | |
| Name TUBB | |
| Synonyms TUBB5 | |
| Function Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain | |
| Cellular Location Cytoplasm, cytoskeleton. | |
| Tissue Location Ubiquitously expressed with highest levels in spleen, thymus and immature brain | |
Beta-Tubulin Antibody - Related products
AP7858a: TBB5 Antibody (N-term)
AP7858b: TBB5 Antibody (C-term)
AP7858c: TBB5 Antibody (Center E111)
AP7858d: TBB5 Antibody (Center S153)
LY11504a: TUBB Over-expression Lysate
BP7858a: TBB5 Antibody (N-term) Blocking Peptide
BP7858b: TBB5 Antibody (C-term) Blocking Peptide
BP7858c: TBB5 Antibody (Center E111) Blocking Peptide
BP7858d: TBB5 Antibody (Center S153) Blocking Peptide
AT4403a: TUBB Antibody (monoclonal) (M04)
Beta-Tubulin Antibody - Application data
-
A. Western blot analysis on HeLa cell lysate using anti- Beta-Tubulin RabPAb (Cat. #AJ1097a).
-
B.Immunofluorescent staining of HeLa cells using anti- Beta-Tubulin Rab pAb (Cat. #AJ1097a)
-
C. Immunohistochemical analysis of paraffin-embedded human muscle using anti-Beta Tubulin Rab pAb (Cat. #AJ1097a)
Beta-Tubulin Antibody - Research Areas
Abgent welcomes feedback from its customers.
If you have used an Abgent product and would like to share how it has performed, please click on the
"Submit Review" button and provide the requested information. Our staff will examine and post your
review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abgent.com.
Thank you for your support.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Microtubules are essential parts in eukaryotic cell structures, transportation, and mitosis and consists mainly of 2 soluble protein subunits, alpha and beta tubulin. Beta-tubulin binds to alpha tubulin to form tubulin heterodimer which is post-translationally modified (1). The tubulin dimer complex binds to GTP and assembles onto the positive ends of microtubules. After incorporation into the microtubules, bound GTP is hydrolyzed by beta tubulin. The stability of the dimer in the microtubules is depended on presence of beta tubulin, where dimer with GTP bound beta-tubulin is stable to microtubule incorporation (2). Mutation on beta-tubulin has been linked to anti-cancer drug resistance in lung cancers (3).
REFERENCES
1. Wang, HW et al. Nature 435: 911-915, 2005.
2. Cleveland, DW et al. Cell 20: 95-105, 1980.
3. Tsurutani J et al. Lung Cancer 35: 11-16, 2002.
