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BM88 Antibody

Rabbit Monoclonal Antibody

  • WB - BM88 Antibody AJ1102a
    Western blot analysis on (A) fetal brain, (B) U87-MG and (C) Neuro-2a cell lysates using anti-BM88 RabMAb (Cat. #AJ1102a).
  • IHC - BM88 Antibody AJ1102a
    Immunohistochemical analysis of paraffin-embedded human brain tissue using anti-BM88 RabMAb (Cat. #AJ1102a).
  • IHC - BM88 Antibody AJ1102a
    Immunohistochemical analysis of paraffin-embedded human glioma tissue using anti-BM88 RabMAb (Cat. #AJ1102a).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8N111
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Monoclonal
Clone Names EPR3739
Calculated MW 14954 Da
Gene ID 51286
Other Names Cell cycle exit and neuronal differentiation protein 1, BM88 antigen, CEND1, BM88
Target/Specificity A synthetic peptide corresponding to residues in human BM88 was used as an immunogen.
Dilution WB~~1:1000
Format 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsBM88 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CEND1
Synonyms BM88
Function Involved in neuroblastoma cell differentiation.
Cellular Location Membrane; Single-pass type IV membrane protein
Tissue Location Neuron specific.
Research Areas
Citations (0)

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BM88 is a neuron-specific protein widely distributed in the nervous system and implicated in cell cycle exit and differentiation of neuronal precursors (1, 2). It is an integral membrane protein, which appears early during brain development and remains at high levels at the mature state (1). It is expressed in terminally differentiated neurons and also in neuronal progenitors, in lower levels. BM88 expression shows a tight correlation with the progression of progenitor cells towards neuronal differentiation (2). BM88 is crucial for the transition from neuroblasts to mature neurons when reaching high levels (3).


1. Mamalaki A, et al. J Biol Chem. 270(23):14201-8, 1995 2. Katsimpardi L, et al. Stem Cells. 26(7):1796-807, 2008 3. Papadodima O, et al. J Neurochem. 95(1):146-59, 2005

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Cat# AJ1102a
(40 western blots)

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