|Calculated MW||18317 Da|
|Other Names||Protein B-Myc, Mycb, Bmyc|
|Target/Specificity||A synthetic peptide corresponding to residues in rat B-Myc was used as an immunogen.|
|Format||50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||b-Myc Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Seems to act as an inhibitor of cellular proliferation.|
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Provided below are standard protocols that you may find useful for product applications.
B-Myc is a member of the myc family of transcriptional regulators including c-myc, N-myc, L-myc and S-myc (1-2). Even though the biological role of B-myc has not yet been determined, B-myc has been show to inhibit c-myc function (3). B-myc is mostly expressed in the brain and protein expression in the adrenal gland, pituitary gland, mammary gland, ovary, and uterus suggest that its gene expression is associated with hormonally regulated tissues (4).
1. Ingvarsson S, et al. Molec Cell Biol 8:3168-3174, 1988.
2. Henriksson M, et al. Academic Press 109
3. Resar LMS, et al. Mol Cell Biol 13:1130
4. Gregory MA, Oncogene 19:4886
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