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Calmodulin Antibody (CaM) (C-term)

Rabbit Monoclonal Antibody

  • WB - Calmodulin Antibody (CaM) (C-term) AJ1118a
    A. Western blot analysis on NIH 3T3 cell lysate using anti-Calmodulin (C-term) RabMAb (Cat. #AJ1118a), dilution 1:5,000
  • IHC - Calmodulin Antibody (CaM) (C-term) AJ1118a
    B. Immunohistochemical analysis of paraffin-embedded human urinary bladder carcinoma using anti-Calmodulin RabMAb (Cat. #AJ1118a).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P62158
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Monoclonal
Clone Names EP799Y
Calculated MW 16838 Da
Gene ID 801;805;808
Other Names Calmodulin, CaM, CALM1, CALM, CAM, CAM1
Target/Specificity A synthetic peptide corresponding to residues in the C-terminus of human Calmodulin was used as immunogen.
Dilution WB~~1:1000~2000
Format 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCalmodulin Antibody (CaM) (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CALM1
Synonyms CALM, CAM, CAM1
Function Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis.
Cellular Location Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=Distributed throughout the cell during interphase, but during mitosis becomes dramatically localized to the spindle poles and the spindle microtubules
Research Areas
Citations ( 0 )


Calmoduin (CaM) is a calcium modulator protein and a transducer of calcium signals (1-2). Upon calcium binding, calmodulin undergoes conformational changes and binds and modulates a diverse array of proteins. Calcium-bound CaM (Ca2+-CaM) can assume a variety of shapes depending on the target (3). Ca2+-CaM binds many kinases, phosphatases, signaling proteins, and structural proteins affecting a wide variety of processes including neurotransmitter release, muscle contraction, metabolism, apoptosis, inflammation, membrane protein organization, and cytoskeleton movement (2, 4-5).


1. Sasagawa T, Ericsson LH, Walsh KA, Schreiber WE, Fischer EH, Titani K. Biochemistry. 1982 May 11;21(10):2565-9.
2. Eldik L.V. and Watterson,D.M. (1998) Academic Press, San Diego, CA
3. Finn B.E., Evenas,J., Drakenberg,T., Waltho,J.P., Thulin,E. and Forsen,S. (1995) Nat. Struct. Biol., 2, 777
4. DeMaria C.D., Soong,T.W., Alseikhan,B.A., Alvania,R.S. and Yue,D.T. (2001) Nature, 411, 484
5. Deisseroth K., Heist,E.K. and Tsien,R.W. (1998) Nature, 392, 198

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Cat# AJ1118a
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