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CD2 Antibody

Rabbit Monoclonal Antibody

  • WB - CD2 Antibody AJ1154a
    Western blot analysis on (A) PBMC and (B) Jurkat cell lysates using anti-CD2 RabMAb (Cat. #AJ1154a).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P06729
Reactivity Human
Host Rabbit
Clonality Monoclonal
Clone Names EPR3693
Calculated MW 39448 Da
Gene ID 914
Other Names T-cell surface antigen CD2, Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor, T-cell surface antigen T11/Leu-5, CD2, CD2, SRBC
Target/Specificity A synthetic peptide corresponding to residues in human CD2 was used as an immunogen.
Dilution WB~~1:1000~5000
Format 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCD2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD2
Synonyms SRBC
Function CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T- cells, the cytoplasmic domain is implicated in the signaling function.
Cellular Location Membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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T-cell surface antigen CD2 (CD2) is a T-cell specific surface glycoprotein that is critically important for mediating adherence of T cells to antigen-presenting cells or target cells (1). It interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, and the cytoplasmic domain is implicated in the signaling function (2). CD2 is one of the largest T-cell markers, being present on more than 95% of thymocytes; it is also found one some natural killer cells but not on B lymphocytes (3).


1. Withka J.M., et al. Structure 1:69-81, 1993 2. The UniProt Consortium, The Universal Protein Resource (UniProt). Nucleic Acids Res. 36:D190-D195 (2008) 3. Sewell, W. A.Proc. Nat. Acad. Sci. 83: 8718-8722, 1986

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Cat# AJ1154a
(40 western blots)
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