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CD5 Antibody

Rabbit Monoclonal Antibody

  • WB - CD5 Antibody AJ1165a
    A.Western blot analysis on PMBC treated with TPA cell lysate using anti-CD5 RabMAb (Cat. #AJ1165a), dilution 1:10,000.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P06127
Reactivity Human
Host Rabbit
Clonality Monoclonal
Clone Names EPR2953
Calculated MW 54578 Da
Gene ID 921
Other Names T-cell surface glycoprotein CD5, Lymphocyte antigen T1/Leu-1, CD5, CD5, LEU1
Target/Specificity A synthetic peptide corresponding to residues in human CD5 was used as an immunogen.
Dilution WB~~1:20000
Format 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCD5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD5
Synonyms LEU1
Function May act as a receptor in regulating T-cell proliferation.
Cellular Location Cell membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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CD5 (Lymphocyte antigen T1/Leu-1) is a transmembrane glycoprotein which has been implicated as a single-pass type I receptor in the regulation of T-cell proliferation (1). CD5 is part of the scavenger receptor cysteine-rich (SRCR) family group B and it is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. CD5 is also expressed by T cell leukemia, lymphomas, activated T cells, and occasionally a subset of B cells. Mantle cell lymphomas (same as diffuse centrocytic lymphomas) are CD5 positive while the follicle center cell lymphomas are CD5 negative. A ligand for CD72/LYB-2, CD5 has been linked to negative regulation of T cell and B cell receptors signaling (2).


1. Spertini F et al. Journal of Immunology, 146(1):47-52,1991
2. Perez-Villar JJ et al. Mol Cell Biol, 19(4):2903-2912, 1999

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Cat# AJ1165a
(40 western blots)
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