- Antibodies
- New
- Biological Process >
- Cellular Compartment >
- Disease >
- Molecular Function >
- Pathway Biocarta >
- Pathway KEGG >
- Pathway Panther >
- Tissue >
- Tag
- Peptides
- Biological Process >
- Cellular Compartment >
- Disease >
- Molecular Function >
- Pathway Biocarta >
- Pathway KEGG >
- Pathway Panther >
- Tissue >
- Amino Acids
- Tag
- Biological Process >
- Proteins
- RNAi
- FL cDNA Clones
- Cell/Tissues/Lysates
CD56/NCAM AntibodyRabbit Monoclonal Antibody
| Country | United States
Ordering Information
Australia Austria Belgium Brazil Bulgaria Canada China Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland India Indonesia Ireland Israel Italy Japan Korea Latvia Lithuania Luxembourg Macedonia Malaysia Malta Netherlands Norway Pakistan Poland Portugal Romania Serbia Singapore Slovakia Slovenia Spain Sweden Switzerland Taiwan Turkey United Kingdom United States Vietnam Others 
|
|||
|---|---|---|---|---|
| Catalog # | Size | Availability | Price | |
| AJ1166a | 100ul 400 ul | 2-3 days | $ 315.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
CD56/NCAM Antibody - Product info | |
| Application | WB, IF, IHC
|
| Primary Accession | P13591 |
| Reactivity | Human |
| Clone Names | EP2567Y |
| Calculated MW | 94574 Da |
| Gene ID 4684 | |
| Other Names NCAM1, NCAM, Neural cell adhesion molecule 1 | |
| Target/Specificity A synthetic peptide corresponding to residues near the C-terminus of human NCAM/CD56 was used as an immunogen. | |
| Dilution WB~~1:500~2000 IHC~~1:500~2000 | |
| Format 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions CD56/NCAM Antibody is for research use only and not for use in diagnostic or therapeutic procedures. | |
CD56/NCAM Antibody - Protein Information | |
| Name NCAM1 | |
| Synonyms NCAM | |
| Function This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc | |
| Cellular Location Isoform 1: Cell membrane; Single-pass type I membrane protein Isoform 3: Cell membrane; Lipid-anchor, GPI- anchor Isoform 5: Secreted. | |
CD56/NCAM Antibody - Related products
AP9470c: NCAM1 Antibody (Center)
CD56/NCAM Antibody - Application data
-
A.Western blot analysis on SH-SY5Y cell lysate using anti-NCAM RabMAb (Cat. #AJ1166a), dilution 1:100,000.
-
B. Immunofluorescent staining of SH-SY5Y cells using anti-NCAM RabMAb (Cat. #AJ1166a).
-
C. Immunohistochemical analysis of paraffin-embedded human astrocytoma using anti-CD56 RabMAb (Cat. #AJ1166a)
CD56/NCAM Antibody - Research Areas
Abgent welcomes feedback from its customers.
If you have used an Abgent product and would like to share how it has performed, please click on the
"Submit Review" button and provide the requested information. Our staff will examine and post your
review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abgent.com.
Thank you for your support.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
The neural cell adhesion molecule (NCAM/CD56) has been shown to mediate homophilic cell-cell adhesion in the neuroendocrine system with interactions among immunoglobulin-like domains. It is a multifunction transmembrane protein involved in synaptic plasticity, neurodevelopment, and neurogenesis. NCAM appears on early embryonic cells and is important in the formation of cell collectives and their boundaries at sites of morphogenesis (1-3). It is preferentially expressed on human NK cells and a subset of T lymphocytes that mediate MHC-unrestricted cell-mediated cytotoxicity (1). Single nucleotide polymorphisms (SNPs) in the NCAM gene are reported to be significantly associated with bipolar disorder in the Japanese population (3).
REFERENCES
1. Lanier LL, et al. J Immunol. 146(12):4421-6, 1991
2. Cunningham BA, et al. Science. 236(4803):799-806, 1987
3. Atz M E, et al. Psychiatr Genet. 17 (2):55-67, 2007
