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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CD56/NCAM Antibody   

CD56/NCAM Antibody

Rabbit Monoclonal Antibody

  • WB - CD56/NCAM Antibody AJ1166a
    A.Western blot analysis on SH-SY5Y cell lysate using anti-NCAM RabMAb (Cat. #AJ1166a), dilution 1:100,000.
  • IF - CD56/NCAM Antibody AJ1166a
    B. Immunofluorescent staining of SH-SY5Y cells using anti-NCAM RabMAb (Cat. #AJ1166a).
  • IHC - CD56/NCAM Antibody AJ1166a
    C. Immunohistochemical analysis of paraffin-embedded human astrocytoma using anti-CD56 RabMAb (Cat. #AJ1166a)
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P13591
Reactivity Human
Host Rabbit
Clonality Monoclonal
Clone Names EP2567Y
Calculated MW 94574 Da
Gene ID 4684
Other Names Neural cell adhesion molecule 1, N-CAM-1, NCAM-1, CD56, NCAM1, NCAM
Target/Specificity A synthetic peptide corresponding to residues near the C-terminus of human NCAM/CD56 was used as an immunogen.
Dilution WB~~1:500~2000
Format 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCD56/NCAM Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NCAM1
Synonyms NCAM
Function This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.
Cellular Location Isoform 1: Cell membrane; Single-pass type I membrane protein Isoform 3: Cell membrane; Lipid-anchor, GPI- anchor Isoform 5: Secreted.
Research Areas
Citations (0)

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The neural cell adhesion molecule (NCAM/CD56) has been shown to mediate homophilic cell-cell adhesion in the neuroendocrine system with interactions among immunoglobulin-like domains. It is a multifunction transmembrane protein involved in synaptic plasticity, neurodevelopment, and neurogenesis. NCAM appears on early embryonic cells and is important in the formation of cell collectives and their boundaries at sites of morphogenesis (1-3). It is preferentially expressed on human NK cells and a subset of T lymphocytes that mediate MHC-unrestricted cell-mediated cytotoxicity (1). Single nucleotide polymorphisms (SNPs) in the NCAM gene are reported to be significantly associated with bipolar disorder in the Japanese population (3).


1. Lanier LL, et al. J Immunol. 146(12):4421-6, 1991
2. Cunningham BA, et al. Science. 236(4803):799-806, 1987
3. Atz M E, et al. Psychiatr Genet. 17 (2):55-67, 2007

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Cat# AJ1166a
(40 western blots)
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