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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CD56/NCAM Antibody   

CD56/NCAM Antibody

Rabbit Monoclonal Antibody

  • WB - CD56/NCAM Antibody AJ1166b
    Western blot analysis on A) SH-SY5Y, B) fetal brain tissue lysates using anti-CD56/NCAM RabMAb (Cat. #AJ1166b).
  • IHC - CD56/NCAM Antibody AJ1166b
    Immunohistochemical analysis of paraffin-embedded human glioma using anti-CD56/NCAM RabMAb (Cat. #AJ1166b).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P13591
Reactivity Human
Host Rabbit
Clonality Monoclonal
Clone Names EPR2566
Calculated MW 94574 Da
Gene ID 4684
Other Names Neural cell adhesion molecule 1, N-CAM-1, NCAM-1, CD56, NCAM1, NCAM
Target/Specificity A synthetic peptide corresponding to residues in extracellular domain of human CD56/NCAM was used as an immunogen.
Dilution WB~~1:10000~50000
Format 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCD56/NCAM Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NCAM1
Synonyms NCAM
Function This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.
Cellular Location Isoform 1: Cell membrane; Single-pass type I membrane protein Isoform 3: Cell membrane; Lipid-anchor, GPI- anchor Isoform 5: Secreted.
Research Areas
Citations (0)

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The neural cell adhesion molecule (NCAM/CD56) is a homophilic binding glycoprotein belonging to immunoglobulin (Ig) superfamily. It is commonly found on the surface of neurons, NK cells, glia, and neuroendocrine tissues, and it is involved in synaptic plasticity, neurodevelopment, and neurogenesis. NCAM mediates axon growth, fasciculation, and cell adhesion by homophilic and heterophilic interactions (1). Due to alternative splicing, at least 27 different isoforms of NCAM mRNAs has been identified, leading to variety of NCAM isoforms (2). Three major NCAM isoforms are: 140 and 180 kDa transmembrane forms (NCAM-140, NCAM-180), and 120 kDa glycophosphatidylinositol (GPI)-linked isoform (NCAM120) (3).


1. BA Cunningham et al., Science 236(4803) 799-806, 1987 2. AA Reyes et al., Mol Cell Biol 11(3): 1654-1661, 1991. 3. HE Beggs et al., JCB 272(13):8310-8319, 1997.

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Cat# AJ1166b
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