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CD90 Antibody

Rabbit Monoclonal Antibody

  • WB - CD90 Antibody AJ1172b
    Western blot analysis on A) human fetal brain tissue lysates, B) human bone marrow lysates using anti-CD90 RabMAb (Cat. #AJ1172b).
  • IHC - CD90 Antibody AJ1172b
    Immunohistochemical analysis of paraffin-embedded human glioma using anti-CD90 RabMAb (Cat. #AJ1172b).
  • IHC - CD90 Antibody AJ1172b
    Immunohistochemical analysis of paraffin-embedded human normal kidney tissue using anti-CD90 RabMAb (Cat. #AJ1172b).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P04216
Reactivity Human
Host Rabbit
Clonality Monoclonal
Clone Names EPR3133
Calculated MW 17935 Da
Gene ID 7070
Other Names Thy-1 membrane glycoprotein, CDw90, Thy-1 antigen, CD90, THY1
Target/Specificity A synthetic peptide corresponding to residues near the N-terminal of human CD90 was used as an immunogen.
Dilution WB~~1:1000~5000
Format 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCD90 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name THY1
Function May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.
Cellular Location Cell membrane; Lipid-anchor, GPI-anchor
Research Areas
Citations (0)

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CD90 (Cluster of Differentiation 90, Thy-1) is a heavily N-glycosylated GPI linked cell surface protein member of the immunoglobulin (Ig) superfamily. As a smallest member of family, CD90 may play a role in cell-to-cell and cell-to-ligand interactions during synaptogensis and other neuron related activities (e.g. neurite outgrowth, nerve regeneration) (1). In developing nervous tissue, CD90 is involved in axon growth regulation by halting axon growth in mature axon via its interaction with intergin-beta-3 on mature astrocytes. Additionally, CD90 has been linked to apoptosis, adhesion, migration, cancer (including cancer stem cells), and fibrosis (2). As a major marker for hematopoietic stem cells (HSCs), CD90 mediates differentiation of HSCs. In stem cancer cell research, CD90 positive cells in the hepatocellular carcinoma (HCC) have been shown to display tumorigenic capacity (3).


1. The UniProt Consortium, The Universal Protein Resource (UniProt). Nucleic Acids Res. 36:D190-D195 (2008) 2. TA Rege, JS Hagood., The FASEB Journal 20:1045-1054, 2006 3. ZF Yang et al., Cancer Cell 3(2):153-66, 2008.

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Cat# AJ1172b
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