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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Fibronectin Antibody   

Fibronectin Antibody

Rabbit Monoclonal Antibody

  • WB - Fibronectin Antibody AJ1297b
    A. Western blot analysis of human serum using anti-Fibronectin RabMAb (Cat. #AJ1297b).
  • IHC - Fibronectin Antibody AJ1297b
    B. Immunohistochemical analysis of paraffin-embedded human uterus using anti-Fibronectin RabMAb (Cat. #AJ1297b).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P02751
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Monoclonal
Clone Names F14
Calculated MW 262625 Da
Gene ID 2335
Other Names Fibronectin, FN, Cold-insoluble globulin, CIG, Anastellin, Ugl-Y1, Ugl-Y2, Ugl-Y3, FN1, FN
Target/Specificity A recombinant protein was used as immunogen.
Dilution WB~~1:10000~50000
Format 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFibronectin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FN1
Synonyms FN
Function Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts.
Cellular Location Secreted, extracellular space, extracellular matrix
Tissue Location Plasma FN (soluble dimeric form) is secreted by hepatocytes. Cellular FN (dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix. Ugl-Y1, Ugl-Y2 and Ugl-Y3 are found in urine.
Research Areas
Citations (0)

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Fibronectins are high molecular weight glycoproteins. Found in plasma or at the cell surface, fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Additionally, binding of fibronectin to collagen, fibrin, heparin, DNA, and actin (1) may trigger key events such as cell migration and repair during the early phases of wound healing (1-3).


1. Yamada,K.M. (1983) Annu. Rev. Biochem., 52, 761-799.
2. Hynes,R.O. and Yamada,K.M. (1982) J. Cell. Biol., 95, 369-377.
3. Skorstengaard,K., Thogersen,H.C., Vibe-Pedersen,K., Petersen,T.E. and Magnusson, S. (1982) Eur. J. Biochem., 128, 605-623

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Cat# AJ1297b
(40 western blots)
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