Register or Login
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   Galectin-3 Antibody   

Galectin-3 Antibody

Rabbit Monoclonal Antibody

  • WB - Galectin-3 Antibody AJ1312b
    A. Western blot analysis on (A) HeLa, (B) SW480, (C) A431 and (D) MCF7 cell lysates using anti-Galectin-3 RabMAb (Cat. #AJ1312b), dilution 1:5000.
  • IHC - Galectin-3 Antibody AJ1312b
    B.Immunohistochemical analysis of paraffin-embedded human ovarian carcinoma using anti-Galectin-3 RabMAb (Cat. #AJ1312b).
  • IF - Galectin-3 Antibody AJ1312b
    C. Immunofluorescent staining of HeLa cells using anti-Galectin-3 RabMAb (Cat. #AJ1312b).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P17931
Reactivity Human, Rat
Host Rabbit
Clonality Monoclonal
Clone Names EPR2774
Calculated MW 26152 Da
Gene ID 3958
Other Names Galectin-3, Gal-3, 35 kDa lectin, Carbohydrate-binding protein 35, CBP 35, Galactose-specific lectin 3, Galactoside-binding protein, GALBP, IgE-binding protein, L-31, Laminin-binding protein, Lectin L-29, Mac-2 antigen, LGALS3, MAC2
Target/Specificity A synthetic peptide corresponding to residues in human Galectin-3 was used as an immunogen.
Dilution WB~~1:500~1000
Format 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGalectin-3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms MAC2
Function Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
Cellular Location Cytoplasm. Nucleus. Secreted. Note=Secreted by a non-classical secretory pathway and associates with the cell surface
Tissue Location A major expression is found in the colonic epithelium. It is also abundant in the activated macrophages Expressed in fetal membranes.
Research Areas
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to, and receive a free "I Love Antibodies" mug.


Galectins are a family of beta-galactoside-binding animal lectins that are associated with diverse cellular events, including immune response. Glectin-3 has previously been identified in rat, mouse and human tissues and is evolutionarily highly conserved. It is an abundant cell-surface component of inflammatory macrophages and their major non-integrin laminin-binding protein. It is also mainly expressed in colonic epithelial cells. Galectin-3 is a cell surface receptor of the advanced glycosylation end products (AGE), which has involvement in the pathogenesis of nephropathy and other diabetic complications (1-2).


1. Henderson NC, et al. Proc Natl Acad Sci 103(13):5060-5,2006
2. Lacobini C, et al. J Am Soc Nephrol 14:S264-S270, 2003

Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at

Cat# AJ1312b
(40 western blots)
Alternative Products:

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanKoreaLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Santa Cruz Alternative
Terms & Conditions