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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Gstk1 Antibody   

Gstk1 Antibody

Rabbit Monoclonal Antibody

  • WB - Gstk1 Antibody AJ1335b
    A.Western blot analysis on (A) fetal liver, (B) human heart, (C) 293T and (D) HeLa cell lysates using anti-Gstk1 RabMAb (Cat. #AJ1335b), dilution 1:10,000.
  • IHC - Gstk1 Antibody AJ1335b
    B.Immunohistochemical analysis of parafin-embedded human liver using anti-Gstk1 RabMAb (Cat. #AJ1335b).
  • IF - Gstk1 Antibody AJ1335b
    C.Immunofluorescent staining of HeLa cells using anti-Gstk1 RabMAb (Cat. #AJ1335b).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y2Q3
Reactivity Human
Host Rabbit
Clonality Monoclonal
Clone Names EPR1939
Calculated MW 25497 Da
Gene ID 373156
Other Names Glutathione S-transferase kappa 1, GST 13-13, GST class-kappa, GSTK1-1, hGSTK1, Glutathione S-transferase subunit 13, GSTK1
Target/Specificity A synthetic peptide corresponding to residues in human Gstk1was used as an immunogen.
Dilution WB~~1:500~5000
Format 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGstk1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GSTK1
Function Significant glutathione conjugating activity is found only with the model substrate, 1-chloro-2,4-dinitrobenzene (CDNB).
Cellular Location Peroxisome.
Tissue Location Ubiquitous..
Research Areas
Citations (0)

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Glutathione transferases (Gst) are a superfamily of enzymes that play a vital functional role in the cellular detoxification process. They catalyze the conjugation of the thiol group of glutathione to the electrophilic groups of a wide range of hydrophobic substrates, leading to an easier removal of the latter from the cells. The kappa class (Gstk) is the least studied one among various classes within the superfamily. The TRX-like domain of Gstk shares 19% sequence identity and structure similarity with the theta class Gst, suggesting that the kappa class is more closely related to the theta class enzyme within the Gst superfamily (1). Research has demonstrated that Gstk1 is expressed at relatively high levels in liver and stomach, and at moderate levels in kidney, heart, large intestine, testis, and lung. Sparse or essentially no Gstk1 protein was reported to be detected in small intestine, brain, spleen, and skeletal muscle (2).


1. Li J, et al. Protein Sci, 14(9):2361-9, 2005
2. Thomson RE, et al. J Histochem Cyto 52(5):653-62, 2004

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Cat# AJ1335b
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