|Calculated MW||40569 Da|
|Other Names||Motor neuron and pancreas homeobox protein 1, Homeobox protein HB9, MNX1, HLXB9|
|Target/Specificity||A synthetic peptide corresponding to residues near the C-terminus of human HB9 was used as an immunogen.|
|Format||50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||HB9/HLXB9 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Putative transcription factor involved in pancreas development and function.|
|Tissue Location||Expressed in lymphoid and pancreatic tissues.|
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Provided below are standard protocols that you may find useful for product applications.
HB9 are sequence-specific DNA-binding proteins that have been implicated in the control of gene expression both in developing as well as in adult tissues; a putative transcription factor involved in pancreas development and function. HB9, was found to be highly expressed in bone marrow cells enriched for CD34-positive cells, present at low levels in unfractionated bone marrow cells, and essentially undetectable in bone marrow cells depleted of CD34 cells. Studies show differentiation of CD34-positive cells along a specific cell lineage likely requires downregulation of both HB24 and HB9 (1).
1. Deguchi Y, et al. Blood 78(2):323-8, 1991
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