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HLF Antibody

Rabbit Monoclonal Antibody

  • WB - HLF Antibody AJ1363a
    Western blot analysis on (A) 293T, (B) SH-SY5Y, (C) HepG2, (D) HeLa , (E) fetal kidney, (F) fetal liver and (G) fetal brain lysates using anti-HLF RabMAb (Cat. #AJ1363a).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q16534
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Monoclonal
Clone Names EPR3645
Calculated MW 33199 Da
Gene ID 3131
Other Names Hepatic leukemia factor, HLF
Target/Specificity A synthetic peptide corresponding to residues near the C-term in human HLF was used as an immunogen.
Dilution WB~~1:500~1000
Format 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHLF Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HLF
Cellular Location Nucleus.
Tissue Location Highly expressed in liver; lower levels in lung and kidney
Citations (0)

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Hepatic leukemia factor (HLF) is a member of the proline and acidic-rich (PAR) protein family, a subset of the bZIP transcription factors (2). It is a transcription factor related to the CES-2 protein, which controls apoptosis of the NSM serotoninergic neurons (1). HLF has been linked to malignancies of the lymphoid system, but is not normally expressed in these cells. HLF transcripts are detected in the liver, kidney, lung and adult nervous system. It plays a role in the function of differentiated neurons in the adult nervous system (1), and it forms homodimers or heterodimers with other PAR family members and binds sequence-specific promoter elements to activate transcription (2).


1. Hitzler JK, et al. Brain Res. 820(1-2):1-11, 1999 2. NCBI Reference Sequence (RefSeq): a curated non- redundant sequence database of genomes, transcripts and proteins Pruitt KD, Tatusova, T, Maglott DR Nucleic Acids Res 2007 Jan 1;35(Database issue):D61-5

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Cat# AJ1363a
(40 western blots)
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