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IL-2 Antibody

Rabbit Monoclonal

  • WB - IL-2 Antibody AJ1397a
    A. Western blot analysis on (A) human thymus and (B) PBMC cell lysates using anti-IL-2 RabMAb (Cat. #AJ1397a).
  • IHC - IL-2 Antibody AJ1397a
    B. Immunohistochemical analysis of paraffin-embedded human tonsil using anti-IL-2 RabMAb (Cat. #AJ1397a).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P60568
Reactivity Human
Host Rabbit
Clonality Monoclonal
Clone Names EPR2780
Calculated MW 17628 Da
Gene ID 3558
Other Names Interleukin-2, IL-2, T-cell growth factor, TCGF, Aldesleukin, IL2
Target/Specificity A synthetic peptide corresponding to residues in human IL-2 was used as an immunogen.
Dilution WB~~1:1000~5000
Format 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsIL-2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IL2
Function Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine- activated killer cells, natural killer cells, and glioma cells.
Cellular Location Secreted.
Research Areas
Citations (0)

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Interleukin-2 (IL-2) is an immunoregulatory cytokine that functions as a growth factor and central regulator in the immune system (1, 2). It participates in modulating the immune response by helping control the rate of clonal expansion of lymphocytes (3). IL-2 acts through a quaternary receptor signaling complex containing alpha, beta, and common gamma chain receptors (1). IL-2 is produced by T-cells in response to antigenic or mitogenic stimulation. It is required for T-cell proliferation and other activities crucial for regulation of the immune response. IL-2 can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (4).


1. Wang X., et al. Science 310:1159-1163, 2005 2. Stauber D.J., et al. Proc. Natl. Acad. Sci. U.S.A. 103:2788-2793, 2006 3. Bamborough P., et al. Structure 2:839-851, 1994 4. The UniProt Consortium, The Universal Protein Resource (UniProt). Nucleic Acids Res. 36:D190-D195, 2008

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Cat# AJ1397a
(40 western blots)
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