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INPP4A Antibody

Rabbit Monoclonal Antibody

  • WB - INPP4A Antibody AJ1406a
    A. Western blot analysis on (A) fetal brain tissue lysate and (B) Jurkat cell lysate using anti-INPP4A RabMAb (Cat. #AJ1406a).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96PE3
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Monoclonal
Clone Names EPR3426
Calculated MW 109956 Da
Gene ID 3631
Other Names Type I inositol 3, 4-bisphosphate 4-phosphatase, Inositol polyphosphate 4-phosphatase type I, INPP4A
Target/Specificity A synthetic peptide corresponding to residues near the C-terminus of human INPP4A was used as an immunogen.
Dilution WB~~1:1000~2000
Format 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsINPP4A Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4- trisphosphate and inositol 3,4-bisphosphate.
Tissue Location Isoform 1 is expressed in the platelets, MEG- 01 megakaryocytes and Jurkat T-cells. Isoform 2 is expressed in the brain.
Research Areas
Citations (0)

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Inositol polyphosphate 4-phosphatase (INPP4A), an enzyme of the inositol phosphate signaling pathway, catalyzes the hydrolysis of the 4-position phosphate of inositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate, and phosphatidylinositol 3,4-bisphosphate (1). Hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate has been implicated in mitogenesis mediated by PDGF receptor, the oxidative burst of neutrophils, and translocation of the glucose transporter to the plasma membrane (2).


1. The UniProt Consortium, The Universal Protein Resource (UniProt), Nucleic Acids Res. 36:D190-D195 (2008)
2. Norris et al. J Biol Chem 270(27):16128-33, 1995

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Cat# AJ1406a
(40 western blots)

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