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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   LDH-B Antibody (Heart Subunit)   

LDH-B Antibody (Heart Subunit)

Rabbit Monoclonal Antibody

  • IHC - LDH-B Antibody (Heart Subunit) AJ1438b
    B.Immunohistochemical analysis of paraffin-embedded human liver carcinoma using anti-LDH-B RabMAb (Cat. #AJ1438b).
  • WB - LDH-B Antibody (Heart Subunit) AJ1438b
    A.Western blot analysis on HeLa cell lysate using anti-LDH-B RabMAb (Cat. #AJ1438b).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P07195
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Monoclonal
Clone Names EP1566Y
Calculated MW 36638 Da
Gene ID 3945
Other Names L-lactate dehydrogenase B chain, LDH-B, LDH heart subunit, LDH-H, Renal carcinoma antigen NY-REN-46, LDHB
Target/Specificity A synthetic peptide corresponding to residues in human LDH-B was used as immunogen.
Dilution IHC~~1:50~1:100
Format 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsLDH-B Antibody (Heart Subunit) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Cellular Location Cytoplasm.
Research Areas
Citations (0)

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Lactate dehydrogenase (LDH) is an ubiquitous enzyme commonly found in wide variety of organisms, including plants and microbes. LDH is involved in the interconversion of the pyruvate and NADH to lactate and NAD+. It is also called Hydroxybutyrate Dehydrogenase (HBD), because it can catalyze the oxidation of hydroxybutyrate (1). In mammals, three types of LDH subunits (35 kDa) are encoded by the genes Ldh-A, Ldh-B, and Ldh-C. All LDH subunits can combine to form various terameric isoenzymes (140 kDa). Lactate dehydrogenase B (LDH-B, heart subunit, LDH-H) is involved in the conversion of L-lactate and NAD to pryruvate and NADH and it is predominantly localized in the heart tissue. Similar to other LDH subunit, LDH-B is considered to be an important marker for germ cell tumor (2).


1. Kopperschlager G et al. J Chromatogr B Biomed Appl. 684(1-2):25-49, 1996.
2. Rodriguez S et al. Oncogene 22(12): 1880-1891, 2003

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Cat# AJ1438b
(40 western blots)
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